RT Journal
A1 Blackmore C, Jurkovich GJ, Linnau KF, Cummings P, Hoffer EK, Rivara FP
T1 ASsessment of volume of hemorrhage and outcome from pelvic fracture
JF Archives of Surgery
JO Archives of Surgery
YR 2003
FD May 1
VO 138
IS 5
SP 504
OP 509
DO 10.1001/archsurg.138.5.504
UL http://dx.doi.org/10.1001/archsurg.138.5.504
AB Hypothesis 
    Measurement of pelvic hemorrhage on computed tomographic (CT) scans can estimate the pelvic fracture component of total patient blood loss and predict the need for angiography.Design 
    Retrospective cohort study.Setting 
    Large level 1 trauma center.Patients 
    We examined data from 759 consecutive, nonreferral blunt trauma patients who sustained pelvic fracture.Main Outcome Measures 
    Pelvic-fracture–specific outcomes included estimation of extraperitoneal pelvic hemorrhage volume from emergency department CT scans and determination of arterial injury from angiograms. General patient outcomes determined from medical record review included transfusion requirement, estimated blood loss, and mortality. Subanalysis was performed on subjects with only pelvic fracture as a source of major hemorrhage (derived from discharge International Classification of Diseases, Ninth Revision, Clinical Modification codes).Results 
    Overall mortality was 96 (13%) of 759 patients. Blood transfusion was given to 418 (55%) patients, and 258 (34%) received 6 or more units in the first 72 hours. Pelvic-fracture–related hemorrhage averaged 149 mL (range, 0-1423 mL). Angiography was performed on 163 patients, of whom 113 had arterial injury. Higher pelvic hemorrhage volumes on CT scans were seen in subjects with pelvic arterial injury demonstrated on angiograms (P<.001). In subjects without another source of major hemorrhage, pelvic CT hemorrhage volumes were strongly associated with transfusion requirement (P<.001). Subjects with large pelvic hemorrhage volumes (>500 mL) were more likely to have pelvic arterial injury (risk ratio, 4.8; 95% confidence interval, 3.0-7.8; P<.001) and require large-volume (≥6 U) transfusions (risk ratio, 4.7; 95% confidence interval, 1.8-12.3; P<.001) than patients with smaller pelvic hemorrhage volumes.Conclusion 
    Pelvic hemorrhage volumes derived from pelvic CT scans were predictors of the need for pelvic arteriography and transfusions.