RT Journal A1 Kim S T1 MOlecular biology of aging JF Archives of Surgery JO Archives of Surgery YR 2003 FD October 1 VO 138 IS 10 SP 1051 OP 1054 DO 10.1001/archsurg.138.10.1051 UL http://dx.doi.org/10.1001/archsurg.138.10.1051 AB Aging seems to reflect a patterned program of decline in functional reserves and a reduced ability to maintain homeostasis. Advances in molecular biology have provided new insights into the process of aging at the cellular level. In this review, a few selected models of aging that illustrate the molecular methods and techniques used in aging research are discussed.