RT Journal A1 Cornwell EE, III T1 SUrgical glove perforation and the risk of surgical site infection—invited critique JF Archives of Surgery JO Archives of Surgery YR 2009 FD June 1 VO 144 IS 6 SP 558 OP 558 DO 10.1001/archsurg.2009.71 UL http://dx.doi.org/10.1001/archsurg.2009.71 AB This 2-year study by Misteli and colleagues relates SSI to the incidence of surgical glove perforation in more than 4100 general surgery patients. Glove perforation occurred in 16.3% of cases and rose dramatically in cases lasting longer than 2 hours (34.0% vs 9.4%). Surgical site infection was identified in 7.5% of the cases in which there was a glove perforation vs 3.9% when there was none. The essence of the study resides in the multivariate logistic regression analysis, by which glove perforation was found to be a significant risk factor for SSI but only in cases in which prophylactic antibiotics were not used.