RT Journal A1 Bird D, Zambuto A, O’Donnell C, et al T1 ADherence to ventilator-associated pneumonia bundle and incidence of ventilator-associated pneumonia in the surgical intensive care unit JF Archives of Surgery JO Archives of Surgery YR 2010 FD May 1 VO 145 IS 5 SP 465 OP 470 DO 10.1001/archsurg.2010.69 UL http://dx.doi.org/10.1001/archsurg.2010.69 AB Objective  To examine the impact of adherence to a ventilator-associated pneumonia (VAP) bundle on the incidence of VAP in our surgical intensive care units (SICUs).Design  Prospectively collected data were retrospectively examined from our Infection Control Committee surveillance database of SICU patients over a 38-month period. Cost of VAP was estimated at $30 000 per patient stay.Setting  Two SICUs at a tertiary care academic level I trauma center.Patients  Ventilated patients admitted to a SICU.Intervention  The Institute for Healthcare Improvement VAP bundle was instituted at the beginning of the study and included head-of-bed elevation, extubation assessment, sedation break, peptic ulcer prophylaxis, and deep vein thrombosis prophylaxis. A daily checklist was considered compliant if all 5 items were performed for each patient.Main Outcome Measures  Patients were assessed for VAP. Staff were assessed for compliance with the VAP bundle.Results  Prior to initiation of the bundle, VAP was seen at a rate of 10.2 cases/1000 ventilator days. Compliance with the VAP bundle increased over the study period from 53% and 63% to 91% and 81% in each respective SICU. The rate of VAP decreased to 3.4 cases/1000 ventilator days. A cost savings of $1.08 million was estimated.Conclusions  Initiation of the VAP bundle is associated with a significantly reduced incidence of VAP in patients in the SICU and with cost savings. Initiation of a VAP bundle protocol is an effective method for VAP reduction when compliance is maintained.