RT Journal A1 Shillcutt SD, Clarke MG, Kingsnorth AN T1 COst-effectiveness of groin hernia surgery in the western region of ghana JF Archives of Surgery JO Archives of Surgery YR 2010 FD October 1 VO 145 IS 10 SP 954 OP 961 DO 10.1001/archsurg.2010.208 UL http://dx.doi.org/10.1001/archsurg.2010.208 AB Objective  To calculate the cost-effectiveness of tension-free inguinal hernia repair with mosquito net mesh in the Western Region of Ghana.Design  Prospective study.Setting  Four district hospitals in the Western Region of Ghana.Patients  A total of 113 referred or presenting patients from rural areas with inguinal hernias of various sizes.Intervention  Lichtenstein method of tension-free repair using mosquito net mesh by European and African surgeons.Main Outcome Measure  Disability-adjusted life-years (DALYs) averted with counterfactual definitions based on precedent and expert opinion.Results  All operations were performed as day cases, with 81 of the patients (71.7%) under local anesthesia and few complications. An average of 9.3 (95% confidence interval [CI], 8.0-10.7) DALYs were averted per person, with a total of 1052 averted in the study. Average cost per patient was $120.02 (95% CI, $117.66-$122.39) from a provider perspective and $102.88 ($88.47-$117.29) from a patient perspective. Cost-effectiveness was $12.88 per DALY averted (95% CI, $10.98-$14.78), which is well below the Ghanaian per capita gross national income ($590). Results were robust to sensitivity analysis and may be refined as further work is done on the burden of disease due to hernias in Africa.Conclusions  Inguinal hernia repair was cost-effective in the Western Region of Ghana through international collaboration. Research in other settings should test the generalizability of results.