RT Journal
A1 HARVEY SC
T1 THe velocity of the growth of fibroblasts in the healing wound
JF Archives of Surgery
JO Archives of Surgery
YR 1929
FD April 1
VO 18
IS 4
SP 1227
OP 1240
DO 10.1001/archsurg.1929.01140130317017
UL http://dx.doi.org/10.1001/archsurg.1929.01140130317017
AB Certain characteristics of the healing of the simple incised, uncomplicated wound are, of course, familiar to the surgeon, and have been so since his kind first intelligently observed such a wound from day to day. Its edges "agglutinate," or become adherent to each other through the clotting of the blood. The strength of this adhesion is not sufficiently great for the first two or three days but that a minimum strain will separate the edges. If such is likely to occur, it is necessary to reinforce the "agglutination" with sutures. In from five to eight days it has become solidified, when, unless the strain on the wound is unusually great, the reinforcing action of the sutures is no longer necessary and they are removed. In from eight to twelve days, the strength of the wound is such that it meets the ordinary exigencies of daily life, and toward the end