RT Journal A1 LEWISON EF T1 BLeeding peptic ulcer JF Archives of Surgery JO Archives of Surgery YR 1949 FD July 1 VO 59 IS 1 SP 37 OP 56 DO 10.1001/archsurg.1949.01240040040002 UL http://dx.doi.org/10.1001/archsurg.1949.01240040040002 AB AMONG the many wound stripes incident to modern civilization perhaps the one which looms most prominent yet remains most perplexing is the problem of peptic ulcer and its perilous complications. About 8,800 persons die annually in the United States alone from the sequelae of peptic ulcer, and massive hemorrhage due to ulcer is a grim contributor to this excessive toll.Recent therapeutic procedures in the treatment of peptic ulcer have produced many changes of opinion. However, there still remains much controversy over the treatment of gastroduodenal bleeding. Is surgery indicated and, if so, for which patients? When is the optimal time to operate and what is the operation of choice? What is the present status of transfusions and parenterally administered fluids? Is morphine contraindicated? Is it best to feed patients promptly or to starve them?What is the current trend in antacid therapy? Are amino acids helpful? Is vagotomy the