RT Journal A1 Cooley DA, Hallman GL, Bloodwell RD, Nora JJ, Leachman RD T1 CArdiac transplantation as palliation of advanced heart disease JF Archives of Surgery JO Archives of Surgery YR 1969 FD May 1 VO 98 IS 5 SP 619 OP 625 DO 10.1001/archsurg.1969.01340110111012 UL http://dx.doi.org/10.1001/archsurg.1969.01340110111012 AB In spite of striking advances in surgical treatment of heart disease, large numbers of patients with acquired cardiac pathologic conditions or congenital anomalies remain uncorrectable. Cardiac transplantation may represent the only feasible form of surgical treatment in these patients. Since May 2, 1968, we have performed 14 human heart transplants, one combined heartlung transplant, and one xenograft using a sheep's heart. This paper details our experience with these patients.Surgical Technique  A median sternotomy is made, heparin administered (3 mg/kg of body weight), and preparations made for cardiopulmonary bypass by cannulation of both superior and inferior venae cava. Metal caval cannulae with angled tips ensure against kinking. A catheter placed in the common femoral artery provides return of arterial blood from the pump oxygenator. In some cases the ascending aorta is preferable, as in an infant with a small femoral artery. The inferior vena cava may be cannulated through the