RT Journal
A1 Raju SS, Grogan JB
T1 EFfect of storage on skin allograft survival
JF Archives of Surgery
JO Archives of Surgery
YR 1969
FD July 1
VO 99
IS 1
SP 100
OP 102
DO 10.1001/archsurg.1969.01340130102020
UL http://dx.doi.org/10.1001/archsurg.1969.01340130102020
AB Skin autografts stored up to three weeks at 4 C are regularly used in surgical practice. With the introduction of antilymphocyte serum (ALS), clinical use of skin allografts has become a practical possibility. In certain situations, such as burns, stored allografts may be superior to autografts, especially from the supply viewpoint. There is no precise information available on the behavior of stored allografts, even though there have been suggestions in the literature1 that the survival time may not be the same as for fresh allografts. Also, several workers have recently demonstrated antigenic changes in skin grafts after apparently simple in vitro manipulations.2-4 In view of these considerations, a systematic study of the survival time of skin allografts stored for various periods of time was undertaken.Materials and Methods 
    Female, adult, Sprague-Dawley rats were used as donors throughout, and female, adult, Long-Evans rats as recipients. Skin was either grafted