RT Journal
A1 Barton CH, Vaziri N, Ness RL, Saiki JK, Mirahmadi KS
T1 CImetidine in the management of metabolic alkalosis induced by nasogastric drainage
JF Archives of Surgery
JO Archives of Surgery
YR 1979
FD January 1
VO 114
IS 1
SP 70
OP 74
DO 10.1001/archsurg.1979.01370250072015
UL http://dx.doi.org/10.1001/archsurg.1979.01370250072015
AB • Metabolic alkalosis resulting from nasogastric drainage is a well recognized and potentially serious clinical problem. In the postoperative patient with acute renal failure, the management of the metabolic alkalosis is particularly difficult, and established modalities of therapy are sometimes ineffective and can be hazardous to the patient. In this article, we report on the successful use of cimetidine (an H2-receptor antagonist) as an adjunct in the treatment of severe metabolic alkalosis in a postsurgical renal failure patient. To our knowledge, this is the first reported successful use of cimetidine in the treatment of metabolic alkalosis due to gastric acid loss.(Arch Surg 114:70-74, 1979)