RT Journal A1 Dekker A, Lloyd JC T1 FIne-needle aspiration biopsy in ampullary and pancreatic carcinoma JF Archives of Surgery JO Archives of Surgery YR 1979 FD May 1 VO 114 IS 5 SP 592 OP 596 DO 10.1001/archsurg.1979.01370290042007 UL http://dx.doi.org/10.1001/archsurg.1979.01370290042007 AB • Cytological verification of the angiographic, sonographic, and/or intraoperative diagnosis of pancreatic or ampullary carcinoma may be achieved by fine-needle aspiration biopsy (FNAB). Fifteen biopsies were done in 13 patients, 12 of whom were thought to have pancreatic carcinoma clinically. The FNAB specimen confirmed this in 11 of them. Also, one equivocal (suspicious), two false-negative, and no false-positive results were recorded. Complications were not seen. In addition, four patients with ampullary carcinoma had pancreatoduodenectomy on the basis of FNAB specimens. Since this method is more accurate and is safer and simpler than the traditional wedge or core biopsy of suspected pancreatic or ampullary tumors, and since it may eliminate the need for laparotomy in selected cases, we consider it the preferred method for immediate diagnosis of these neoplasms.(Arch Surg 114:592-596, 1979)