RT Journal
A1 Minton JP, Hamilton W, Sardi A, Nieroda C, Sickle-Santanello B, O'Dwyer PJ
T1 REsults of surgical excision of one to 13 hepatic metastases in 98 consecutive patients
JF Archives of Surgery
JO Archives of Surgery
YR 1989
FD January 1
VO 124
IS 1
SP 46
OP 48
DO 10.1001/archsurg.1989.01410010052012
UL http://dx.doi.org/10.1001/archsurg.1989.01410010052012
AB • Metastatic carcinoma to the liver is generally considered to be associated with a poor prognosis, with five-year survival of only 20% to 30% after resection of solitary lesions. Ninety-eight consecutive patients underwent the surgical removal of one to 13 metastatic lesions from the liver. A rising carcinoembryonic antigen level was considered an indication for reexploration. All gross tumor was removed in every patient; 66 had more than one metastasis. Survival was unexpectedly high: 91 of 98 were alive at 12 months, 50 (70%) of 71 at 13 to 24 months, 23 (66%) of 36 at 25 to 36 months, 14 (74%) of 19 at 37 to 48 months, six (60%) of ten at 49 to 60 months, four (80%) of five at 61 to 72 months, and two (50%) of four 73 to 84 months after resection of multiple liver metastases. The procedure appears to be a safe and, in some patients, beneficial surgical technique for the removal of multiple hepatic metastases.(Arch Surg 1989;124:46-48)