RT Journal A1 Prehn RT, Prehn LM T1 THe flip side of tumor immunity JF Archives of Surgery JO Archives of Surgery YR 1989 FD January 1 VO 124 IS 1 SP 102 OP 106 DO 10.1001/archsurg.1989.01410010112022 UL http://dx.doi.org/10.1001/archsurg.1989.01410010112022 AB • A large amount of data suggest that tumors are, to some degree, dependent for their growth on a positive level of immune reaction, a level that is unique for each tumor. Each tumor gradually adjusts its immunogenicity to the level that will, in the immunologic context of its own particular host, maximize its growth. Thus, it follows that immunosuppression may be as likely as immunoaugmentation to have a therapeutic effect.(Arch Surg 1989;124:102-106)