RT Journal A1 Nava HR, Schuh ME, Nambisan R, Clark JL, Douglass HO, Jr T1 ENdoscopic ablation of esophageal malignancies with the neodymium-yag laser and electrofulguration JF Archives of Surgery JO Archives of Surgery YR 1989 FD February 1 VO 124 IS 2 SP 225 OP 228 DO 10.1001/archsurg.1989.01410020099016 UL http://dx.doi.org/10.1001/archsurg.1989.01410020099016 AB • The case reports of 40 patients with obstructive esophageal cancer treated with electrofulguration (EF) or neodymium (Nd)-YAG laser were reviewed. Surgery was contraindicated because of advanced carcinoma (17 patients), recurrence after resection (13 patients), recurrence after irradiation (four patients), and poor medical condition (four). Two patients refused surgery. There were 31 men and four women; mean age was 62 years. There were 31 adenocarcinomas, eight squamous cell carcinomas, and one metastatic breast carcinoma. Tumor locations were lower esophagus in 35 patients, middle esophagus in three, and cervical esophagus in two. Thirty-five patients had obstructions; two, bleeding, and three, both. None of the patients could swallow solids. A total of 255 treatments were given (mean, 6.6 per patient). The mean number of Nd-YAG treatments was 1.9; for EF, 1.3. All 40 patients tolerated solid food after treatment and the esophagus remained open from three to 14 weeks. Mean survival from first treatment was 11 months; from diagnosis, 17 months. Both techniques were safe and effective.(Arch Surg 1989;149:225-228)