RT Journal
A1 Werbel GB, Nelson SP, Robinson PG, Anastasi J, Joehl RJ, Rege RV
T1 A foregut carcinoid tumor causing zollinger-ellison syndrome
JF Archives of Surgery
JO Archives of Surgery
YR 1989
FD March 1
VO 124
IS 3
SP 381
OP 384
DO 10.1001/archsurg.1989.01410030131022
UL http://dx.doi.org/10.1001/archsurg.1989.01410030131022
AB • A patient had severe peptic ulcer disease complicated by gastric outlet obstruction and choledochoduodenal fistula. Serum gastrin levels were elevated preoperatively to 340 ng/L. A 1.5-cm histologically benign carcinoid tumor of the antrum of the stomach was found at surgery, and surgical resection of the tumor resulted in normalization of serum gastrin levels and amelioration of the peptic acid diathesis. The patient remains asymptomatic at one year. Immunohistochemical staining demonstrated that the carcinoid indeed contained gastrin along with chromogranin, cholecystokinin, and neuron-specific enolase. This is a case of Zollinger-Ellison syndrome caused by a benign foregut carcinoid (gastric carcinoid-gastrinoma).(Arch Surg 1989;124:381-384)