RT Journal A1 Karakousis CP, Emrich LJ, Vesper DS T1 SOft-tissue sarcomas of the proximal lower extremity JF Archives of Surgery JO Archives of Surgery YR 1989 FD November 1 VO 124 IS 11 SP 1297 OP 1300 DO 10.1001/archsurg.1989.01410110055011 UL http://dx.doi.org/10.1001/archsurg.1989.01410110055011 AB • Of 54 patients with soft-tissue sarcomas of the proximal part of the lower extremity, 2 patients (4%) were treated with amputation, while 52 patients (96%) were treated with limb-preserving resection. Adjuvant postoperative irradiation was applied selectively when the minimum margin was less than 2 cm (22 patients). Technical improvements in exposure, resection of involved vessels or nerve, and preservation of function permitted a high rate of limb salvage with satisfactory function. At a median follow-up of 30 months for those subjects still alive, the 5-year disease-free survival rate was 65%, and only 3 patients (6%) had had a local recurrence.(Arch Surg. 1989;124:1297-1300)