RT Journal
A1 Lee SL, Sydorak RM, Chiu VY, Hsu J, Applebaum H, Haigh PI
T1 LOng-term antireflux medication use following pediatric nissen fundoplication
JF Archives of Surgery
JO Archives of Surgery
YR 2008
FD September 15
VO 143
IS 9
SP 873
OP 876
DO 10.1001/archsurg.143.9.873
UL http://dx.doi.org/10.1001/archsurg.143.9.873
AB Hypothesis 
    Nissen fundoplication decreases the use of antireflux medications.Design 
    Retrospective cohort study using discharge abstract data and pharmacy data.Setting 
    Twelve regional Kaiser Permanente hospitals in southern California.Patients 
    Three hundred forty-two patients underwent Nissen fundoplication.Intervention 
    Nissen fundoplication.Main Outcome Measure 
    Use of antireflux medications.Results 
    The number of patients requiring antireflux medications decreased from 233 patients (68.1%) before Nissen fundoplication to 197 (57.6%) after Nissen fundoplication. Of the 233 patients, 176 (75.6%) were restarted on antireflux medications within 1 year after Nissen fundoplication. Use of antireflux medication decreased in neurologically healthy patients but was unchanged in neurologically impaired children.Conclusions 
    Use of antireflux medication decreased after Nissen fundoplication. Neurologically healthy children showed the biggest decrease in antireflux medication use after Nissen fundoplication.