TY - JOUR T1 - Propensity score methods: Setting the score straight—reply AU - Hemmila M Y1 - 2011/07/01 N1 - 10.1001/archsurg.2011.160 JO - Archives of Surgery SP - 887 EP - 889 VL - 146 IS - 7 N2 - P values are numbers. Significance is set by the investigator, and a P value less than the set point for significance allows for rejection of the null hypothesis. Interpreting smaller P values as impressive is potentially misguided.1 A relevant criticism of P values is whether a very high significance value yields any practical implications. As Mayo and Pawlik point out, a finding with a high degree of statistical significance could be of very little use to patients, and clinically meaningful differences might be overlooked because they do not meet the arbitrary cutoff. A likely better representation of the precision of the statistical estimate is to use a 95% confidence interval. SN - 0004-0010 M3 - doi: 10.1001/archsurg.2011.160 UR - http://dx.doi.org/10.1001/archsurg.2011.160 ER -