TY - JOUR T1 - SPlenic vein–inferior mesenteric vein anastomosis to lessen left-sided portal hypertension after pancreaticoduodenectomy with concomitant vascular resection AU - Ferreira N, Oussoultzoglou E, Fuchshuber P, et al Y1 - 2011/12/01 N1 - 10.1001/archsurg.2011.688 JO - Archives of Surgery SP - 1375 EP - 1381 VL - 146 IS - 12 N2 - Hypothesis  A splenic vein (SV)–inferior mesenteric vein (IMV) anastomosis reduces congestion of the stomach and spleen after pancreaticoduodenectomy with resection of the SV–mesenteric vein confluence but carries a risk of left-sided venous hypertension.Design  Comparative retrospective study.Setting  Department of Digestive Surgery and Transplantation, University of Strasbourg, Strasbourg, France.Patients  From January 1, 2002, to February 28, 2010, 39 patients underwent pancreaticoduodenectomy with resection of the SV–mesenteric vein confluence for pancreatic adenocarcinoma. All patients had a terminoterminal portal vein–superior mesenteric vein anastomosis. The SV blood flow into the portal vein was preserved in 11 patients by reimplantation of the SV into the portal vein. Sixteen patients underwent surgical reconstruction of the SV-IMV confluence by anastomosis (group 1), and in 12 patients the natural SV-IMV confluence was preserved (group 2).Main Outcome Measures  Preoperative and postoperative spleen volume and platelet count.Results  Demographic characteristics, preoperative tumor staging, pathological outcome, and postoperative complications were comparable in both groups. There was no difference in platelet count between groups 1 and 2 preoperatively (mean [SD], 293.13 [125.37] vs 241.09 [49.12] × 103/μL [to convert to ×109/L, multiply by 1.0], respectively; P = .21) or postoperatively (mean [SD], 231.75 [156.39] vs 164.31 [76.46] × 103/μL, respectively; P = .32). Likewise, no difference was found in the spleen volume preoperatively (mean [SD], 258.96 [179.23] vs 237.31 [122.46] mL, respectively; P = .76) and on postoperative day 15 (mean [SD], 279.08 [158.10] vs 299.12 [153.11] mL, respectively; P = .78).Conclusion  Early assessment shows that SV-IMV anastomosis is as feasible and as safe as the preservation of a natural SV-IMV confluence in patients undergoing pancreaticoduodenectomy with vascular resection for pancreatic head adenocarcinoma. SN - 0004-0010 M3 - doi: 10.1001/archsurg.2011.688 UR - http://dx.doi.org/10.1001/archsurg.2011.688 ER -