TY  - JOUR
T1  - The time has come to redefine the classic symptoms of primary hyperparathyroidism: Comment on “parathyroidectomy, elevated depression scores, and suicidal ideation in patients with primary hyperparathyroidism”
AU  - Pasieka JL
Y1  - 2013/02/01
N1  - 10.1001/2013.jamasurg.328
JO  - JAMA Surgery
SP  - 115
EP  - 116
VL  - 148
IS  - 2
N2  - 
Hyperparathyroidism today is a biochemical diagnosis and diagnosed much earlier, with less than 20% of patients displaying these classic symptoms. This has led many authors to use the term asymptomatic pHPT for the remaining 80%. Yet, in the last decade, surgeons have contested that very few patients are truly asymptomatic and many benefit from surgery. At first, it was retrospective reflection by patients, claiming how much better they felt following surgery. Then came the patient-based questionnaires and generic quality of life instruments. However, plagued by small series, lack of control groups, and conflicting data from the 3 randomized trials in this field, widespread acceptance of the existence of vague neuropsychologic symptoms in pHPT and their reversibility with surgery has not been forthcoming.1

SN  - 2168-6254
M3  - doi: 10.1001/2013.jamasurg.328
UR  - http://dx.doi.org/10.1001/2013.jamasurg.328
ER  -