TY - JOUR T1 - IMproved survival in congenital diaphragmatic hernia with evolving therapeutic strategies—invited commentary AU - Cilley RE Y1 - 1998/05/01 N1 - 10.1001/archsurg.133.5.503 JO - Archives of Surgery SP - 503 EP - 503 VL - 133 IS - 5 N2 - The implications of these observations leave a number of unanswered questions. These include: (1) Should CDH repair ever be performed at institutions where ECMO is not available? (2) Should all women known to be carrying a fetus with CDH plan to deliver in such centers? (3) Is it ever appropriate to operate immediately after birth on an infant with CDH? (4) May repair be delayed for longer periods than the 2 to 5 days that the authors suggest? (5) In high-risk patients who require immediate ECMO support, must CDH repair always be performed while the patient is receiving ECMO as the authors have practiced, or may CDH repair be delayed until ECMO treatment has been completed? (6) Are there any infants with CDH who are "too sick" to survive and for whom no therapy should be offered? (7) With reports of improved survival rates using conventional postnatal therapy, what, if any, is the role of fetal therapy in the treatment of CDH? SN - 0004-0010 M3 - doi: 10.1001/archsurg.133.5.503 UR - http://dx.doi.org/10.1001/archsurg.133.5.503 ER -