TY  - JOUR
T1  - ANtireflux surgery enhances gastric emptying
AU  - Viljakka M, Saali K, Koskinen M, et al
Y1  - 1999/01/01
N1  - 10.1001/archsurg.134.1.18
JO  - Archives of Surgery
SP  - 18
EP  - 21
VL  - 134
IS  - 1
N2  - Objective 
    To evaluate the influence of antireflux surgery on gastric emptying.Design 
    Nonrandomized controlled trial 3 months before and after surgical intervention.Setting 
    Secondary and tertiary referral center.Patients and Control Subjects 
    Twenty consecutive patients (7 women, 13 men), mean age 49.2 years, with symptomatic, objectively confirmed gastroesophageal reflux disease and 10 healthy control subjects (3 women, 7 men), mean age 37.3 years.Intervention 
    Laparoscopic or open Nissen fundoplication (in 1 case Toupet 180° posterior hemifundoplication).Main Outcome Measures 
    Gastric emptying scintigraphy, using solid food, in control subjects and patients 3 months before and 3 months after the operation; time to halving of the maximal activity and the activity remaining at 60, 100, and 120 minutes.Results 
    Preoperative symptoms included pyrosis in 19 of 20 patients and regurgitation in 18. Three months postoperatively, 19 patients were symptom-free. The mean time to halving of the maximal activity decreased from 113 to 78 minutes (P=.001). Delayed gastric emptying was found postoperatively in 3 patients, compared with preoperative values, using activity at 60, 100, 120 minutes and the mean time to halving of the maximal activity as the variables. Compared with control subjects, gastric emptying was slower in patients preoperatively and faster postoperatively, but the difference was not statistically significant.Conclusion 
    Gastric emptying is enhanced after antireflux surgery, along with cessation of symptoms and healing of esophagitis.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.134.1.18
UR  - http://dx.doi.org/10.1001/archsurg.134.1.18
ER  -