TY  - JOUR
T1  - ENdoscopic ultrasound and fine needle aspiration for the evaluation of pancreatic masses
AU  - Suits J, Frazee R, Erickson RA
Y1  - 1999/06/01
N1  - 10.1001/archsurg.134.6.639
JO  - Archives of Surgery
SP  - 639
EP  - 643
VL  - 134
IS  - 6
N2  - Hypothesis: 
    Endoscopic ultrasound (EUS) and endoscopic ultrasound–guided fine needle aspiration (EUS-FNA) are accurate for the preoperative staging of pancreatic ductal carcinoma.Design 
    Retrospective medical record review.Patients 
    A prospective registry of 98 patients having EUS-FNA for peripancreatic masses from April 1994 to April 1998 was analyzed.Main Outcome Measure 
    The accuracy of EUS-FNA for preoperative diagnosis and staging of peripancreatic neoplasms.Results 
    Ninety-eight patients, aged 41 to 91 years (mean age, 67 years) with peripancreatic masses were evaluated by EUS-FNA. All patients had initial computed tomography scanning with a mass seen in 49 patients, "fullness" to the pancreas in 28 patients, and no mass seen in 21 patients. Evaluation with EUS-FNA revealed 22 benign lesions, 18 T2 masses, 37 T3 masses, 1 T4 mass, and 20 masses representing nonpancreatic tumors. Results of EUS-FNA of adjacent lymph nodes were positive in 27 patients. Twenty-seven patients had surgical resection or palliation permitting operative and pathologic staging. On comparison of EUS-FNA staging with surgical staging, 12 patients were the same stage, 14 patients were upstaged, and 1 patient was downstaged. The remaining patients who did not have surgery have been followed up for a mean of 15 months. Overall accuracy of EUS-FNA for differentiating benign from malignant masses was 96%.Conclusions 
    Endoscopic ultrasound–guided fine needle aspiration is a useful technique for the evaluation of pancreatic masses. It is highly accurate for differentiating between benign and malignant lesions and for predicting T stage, but is limited for predicting nodal status.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.134.6.639
UR  - http://dx.doi.org/10.1001/archsurg.134.6.639
ER  -