TY  - JOUR
T1  - LOcal excision of rectal carcinoma
AU  - Varma MG, Rogers SJ, Schrock TR, Welton ML
Y1  - 1999/08/01
N1  - 10.1001/archsurg.134.8.863
JO  - Archives of Surgery
SP  - 863
EP  - 868
VL  - 134
IS  - 8
N2  - Hypothesis 
    Selected clinicopathologic characteristics of locally treated rectal cancers are predictive of recurrence.Design 
    Case series review with median follow-up of 6 years.Setting 
    University medical center.Patients 
    Fifty-eight patients with rectal cancer who underwent local excisions from February 1, 1982, to December 31, 1998.Main Outcome Measures 
    Local and distant recurrence rates and overall survival.Results 
    Overall local recurrence rate was 14% (8 patients). There were no local recurrences among patients treated with chemotherapy or radiation. Of patients not treated, local recurrence rates were 33%, 5%, 45%, and 25% for T0, T1, T2, and T3 tumors, respectively. No clinicopathologic factor predicted local recurrence. Two patients developed distant recurrence. Overall survival was 98%, 93%, and 84% at 1, 3, and 5 years, respectively.Conclusion 
    In selected patients, outcomes for local excision combined with additional therapy may be equivalent to those for radical resection.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.134.8.863
UR  - http://dx.doi.org/10.1001/archsurg.134.8.863
ER  -