TY  - JOUR
T1  - LOcalization of insulinomas
AU  - Boukhman MP, Karam JM, Shaver J, Siperstein AE, DeLorimier AA, Clark OH
Y1  - 1999/08/01
N1  - 10.1001/archsurg.134.8.818
JO  - Archives of Surgery
SP  - 818
EP  - 823
VL  - 134
IS  - 8
N2  - Hypothesis 
    Intraoperative ultrasonography is more sensitive than preoperative and other intraoperative techniques for localizing insulinoma.Design 
    Retrospective review.Setting 
    A tertiary referral center.Patients 
    All patients with a biochemical diagnosis of organic hyperinsulinism who were referred to University of California, San Francisco, from 1975 to 1998.Methods 
    Sensitivities of the localization techniques for insulinoma were evaluated.Results 
    The sensitivities of tumor localization with arteriography, computed tomography, preoperative ultrasonography, magnetic resonance imaging, magnetic resonance imaging with gadolinium, transhepatic venous sampling, palpation, and intraoperative ultrasonography were 47%, 24%, 50%, 30%, 40%, 55%, 76%, and 91%, respectively. Nine of the 11 nonpalpable and nonvisible tumors at operation were localized by intraoperative ultrasonography.Conclusion 
    The currently available preoperative localization tests are not reliable enough to be recommended when intraoperative ultrasonography is available.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.134.8.818
UR  - http://dx.doi.org/10.1001/archsurg.134.8.818
ER  -