TY  - JOUR
T1  - Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome
AU  - Nwariaku FE, Miller BS, Auchus R, et al
Y1  - 2006/05/01
N1  - 10.1001/archsurg.141.5.497
JO  - Archives of Surgery
SP  - 497
EP  - 503
VL  - 141
IS  - 5
N2  - Hypothesis 
    Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism.Design 
    Retrospective review.Setting 
    University medical center.Patients 
    Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism.Main Outcome Measures 
    We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes.Results 
    Mean ± SEM adrenal nodule size was 1.54 ± 0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia.Conclusion 
    Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.141.5.497
UR  - http://dx.doi.org/10.1001/archsurg.141.5.497
ER  -