TY - JOUR T1 - OPen or laparoscopic resection of a large gastric gastrointestinal stromal tumor—reply AU - Harold KL, Huguet KL, Rush RM, Jr, et al Y1 - 2009/02/01 N1 - 10.1001/archsurg.2008.554 JO - Archives of Surgery SP - 193 EP - 197 VL - 144 IS - 2 N2 - Avoidance of tumor rupture is of utmost importance during GIST resection. Tumors in difficult locations can be manipulated by use of nontraumatic graspers on the stomach wall near the tumor, avoiding direct tumor manipulation. Alternatively, a stitch can be placed near the tumor in normal tissue for retraction. We will typically approach GIST tumors with invasion into adjacent organs through an open operation, though we may begin with diagnostic laparoscopy to confirm invasion that is suspected on preoperative imaging. SN - 0004-0010 M3 - doi: 10.1001/archsurg.2008.554 UR - http://dx.doi.org/10.1001/archsurg.2008.554 ER -