TY  - JOUR
T1  - ONe hundred two patients with pheochromocytoma treated at a single institution since the introduction of laparoscopic adrenalectomy
AU  - Shen WT, Grogan R, Vriens M, Clark OH, Duh Q
Y1  - 2010/09/01
N1  - 10.1001/archsurg.2010.159
JO  - Archives of Surgery
SP  - 893
EP  - 897
VL  - 145
IS  - 9
N2  - Hypothesis 
    Pheochromocytoma can be safely treated laparoscopically; “subclinical” pheochromocytoma is increasingly common.Design 
    Retrospective review.Setting 
    University hospital.Patients 
    Patients undergoing adrenalectomy for pheochromocytoma at our institution in 1994 to 2009.Interventions 
    Laparoscopic, hand-assisted, and open adrenalectomy.Main Outcome Measures 
    Preoperative and postoperative clinical and biochemical data.Results 
    One hundred two patients (52 women, 50 men) with pheochromocytoma underwent 108 operations. Ninety-seven operations were laparoscopic; 7, open; and 4, converted from laparoscopic to hand assisted or open. Six operations were bilateral; 3 were subtotal cortex-sparing resections. Thirty-four patients (33%) presented with adrenal incidentaloma and minimal symptoms, 28 within the past decade. Ten patients had paragangliomas, 7 of whom underwent laparoscopic resection. The mean (SD) tumor size was 5.3 (2.8) cm. Seven patients had recurrence requiring reoperation; the mean length of time between initial operation and recurrence was 6 years (range, 6 months to 17 years). There were no perioperative deaths.Conclusions 
    Laparoscopic adrenalectomy can be safely performed for pheochromocytoma in more than 90% of cases. More than one-third of patients presented with subclinical pheochromocytoma. Patients should be followed up closely because recurrence may develop several years after adrenalectomy.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.2010.159
UR  - http://dx.doi.org/10.1001/archsurg.2010.159
ER  -