TY - JOUR T1 - COst-effectiveness of groin hernia surgery in the western region of ghana AU - Shillcutt SD, Clarke MG, Kingsnorth AN Y1 - 2010/10/01 N1 - 10.1001/archsurg.2010.208 JO - Archives of Surgery SP - 954 EP - 961 VL - 145 IS - 10 N2 - Objective  To calculate the cost-effectiveness of tension-free inguinal hernia repair with mosquito net mesh in the Western Region of Ghana.Design  Prospective study.Setting  Four district hospitals in the Western Region of Ghana.Patients  A total of 113 referred or presenting patients from rural areas with inguinal hernias of various sizes.Intervention  Lichtenstein method of tension-free repair using mosquito net mesh by European and African surgeons.Main Outcome Measure  Disability-adjusted life-years (DALYs) averted with counterfactual definitions based on precedent and expert opinion.Results  All operations were performed as day cases, with 81 of the patients (71.7%) under local anesthesia and few complications. An average of 9.3 (95% confidence interval [CI], 8.0-10.7) DALYs were averted per person, with a total of 1052 averted in the study. Average cost per patient was $120.02 (95% CI, $117.66-$122.39) from a provider perspective and $102.88 ($88.47-$117.29) from a patient perspective. Cost-effectiveness was $12.88 per DALY averted (95% CI, $10.98-$14.78), which is well below the Ghanaian per capita gross national income ($590). Results were robust to sensitivity analysis and may be refined as further work is done on the burden of disease due to hernias in Africa.Conclusions  Inguinal hernia repair was cost-effective in the Western Region of Ghana through international collaboration. Research in other settings should test the generalizability of results. SN - 0004-0010 M3 - doi: 10.1001/archsurg.2010.208 UR - http://dx.doi.org/10.1001/archsurg.2010.208 ER -