TY  - JOUR
T1  - EValuation of the role of magnetic resonance spectroscopy in the diagnosis of follicular malignancies of thyroid
AU  - Gupta N, Goswami B, Chowdhury V, RaviShankar LL, Kakar A
Y1  - 2011/02/01
N1  - 10.1001/archsurg.2010.345
JO  - Archives of Surgery
SP  - 179
EP  - 182
VL  - 146
IS  - 2
N2  - Objectives 
    To evaluate role of magnetic resonance spectroscopy in differentiating benign from malignant follicular nodules.Design 
    Prospective study.Setting 
    Department of Surgery in collaboration with Department of Radio Diagnosis, Maulana Azad Medical College, Delhi, India.Patients 
    Twenty-five patients with a solitary thyroid nodule with follicular etiology.Interventions 
    Magnetic resonance spectroscopy was carried out in all the cases, and its findings were compared with the final diagnosis based on histopathological examination of sample obtained at surgery.Main Outcome Measures 
    Choline peak detected on MRS.Results 
    There were 17 benign cases, 16 follicular adenomas, and 1 colloid goiter. Of the 17 benign cases, only 1 showed choline peak; however, all 8 follicular carcinoma cases showed prominent choline peak. Hence, the sensitivity is 100% while the specificity is 94.11%.Conclusion 
    Magnetic resonance spectroscopy may prove to be a sensitive diagnostic tool in differentiating follicular adenomas from carcinomas.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.2010.345
UR  - http://dx.doi.org/10.1001/archsurg.2010.345
ER  -