TY - JOUR T1 - COmplication rates for percutaneous lower extremity arterial antegrade access AU - Wheatley BJ, Mansour M, Grossman P, et al Y1 - 2011/04/01 N1 - 10.1001/archsurg.2011.47 JO - Archives of Surgery SP - 432 EP - 435 VL - 146 IS - 4 N2 - Hypothesis  The antegrade access (AA) for percutaneous arterial interventions is associated with a higher complication rate than is the retrograde access (RA).Design  Retrospective case review.Setting  A statewide consortium for peripheral vascular interventions consisting of 13 Michigan hospitals collecting data on their endovascular procedures.Patients  Demographic and procedure data on all patients receiving a percutaneous peripheral arterial intervention were entered prospectively by a full-time clinical nurse specialist in each hospital site.Main Outcome Measures  We evaluated vascular complications as a composite of retroperitoneal hematoma, pseudoaneurysm, hematoma requiring blood transfusion, arteriovenous fistula, acute thrombosis, or the need for surgical repair of the access site.Results  In a 2-year period, we collected 6343 cases, of which 5918 had complete data regarding arterial access; of these, 745 (12.6%) were performed via an AA. There were fewer women and smokers (P < .001) in the AA group but more diabetic patients (P < .001). The indications for intervention were more frequently rest pain (P < .001) and limb salvage (P < .001) in the AA group. Multivariate regression analysis showed that the odds of complications were significantly higher with a larger sheath (95% confidence interval, 1.53-4.06; P < .001). Also, the incidence of blood transfusion and subsequent amputation was significantly higher in the AA group (P < .001).Conclusion  Endovascular procedures performed via an AA are more likely to result in perioperative complications and therefore should be used cautiously. SN - 0004-0010 M3 - doi: 10.1001/archsurg.2011.47 UR - http://dx.doi.org/10.1001/archsurg.2011.47 ER -