TY - JOUR T1 - EXperimental peritonitis and peritoneal immunity AU - HERRMANN SF Y1 - 1929/05/01 N1 - 10.1001/archsurg.1929.01140140158009 JO - Archives of Surgery SP - 2202 EP - 2215 VL - 18 IS - 5 N2 - Whenever the bowel must be incised or resected, absolute asepsis cannot be maintained, and peritonitis is still a relatively common postoperative complication. New methods of preventing peritonitis must be developed. Experimental investigation in this field has been greatly hampered by the difficulty of producing peritonitis experimentally. No one has yet been able to reproduce at will a uniform type of peritonitis comparable to the clinical condition as it occurs in man. Obviously, when the fundamental factors on which the development of a disease depends are so little understood, one may expect little progress in its prevention. My experiments were undertaken for the purpose of investigating these fundamental factors. My original purpose was to study the causes of death in peritonitis. It soon became apparent, however, that an understanding must first be gained of the factors by which experimental peritonitis may be produced. This study then led to a consideration of SN - 0272-5533 M3 - doi: 10.1001/archsurg.1929.01140140158009 UR - http://dx.doi.org/10.1001/archsurg.1929.01140140158009 ER -