TY  - JOUR
T1  - CApillary permeability and inflammation in narcotized rabbits
AU  - CRESSMAN RD, RIGDON RH
Y1  - 1939/10/01
N1  - 10.1001/archsurg.1939.01200160076005
JO  - Archives of Surgery
SP  - 586
EP  - 595
VL  - 39
IS  - 4
N2  - A difference in the response of narcotized and of normal animals has been observed in anaphylactic shock. Besredka1 found that sensitized guinea pigs which received the shocking reinjection while under ether anesthesia showed no anaphylactic symptoms. Banzhaf and Famulener2 obtained similar results with chloral hydrate. Farmer3 recently has shown that ethyl carbamate (urethane) administered to sensitized guinea pigs prior to the shocking reinjection led to the survival of 15 of 30 animals. Besredka explained the action of the narcotic by assuming that the ether "allowed the nerve cell to remain indifferent to the union" of the antigen and antibody. Farmer, however, stated the opinion that this effect of a narcotic is probably attributable to its peripheral action on the bronchial musculature. The exact mechanism by which anesthesia may alter the animal's reaction is apparently not clearly understood.Dale and Laidlaw4 have pointed out that rabbits under
SN  - 0272-5533
M3  - doi: 10.1001/archsurg.1939.01200160076005
UR  - http://dx.doi.org/10.1001/archsurg.1939.01200160076005
ER  -