TY - JOUR T1 - RElationship of peptic esophagitis to spontaneous rupture of esophagus AU - DORSEY JM, HOHF RP, LYNN TE Y1 - 1959/06/01 N1 - 10.1001/archsurg.1959.04320060066009 JO - A.M.A. Archives of Surgery SP - 878 EP - 888 VL - 78 IS - 6 N2 - Spontaneous rupture of the esophagus is a serious, and often fatal, condition unless there is prompt surgical intervention. The onset of symptoms is usually abrupt and almost always related to an episode of vomiting. The most frequent site of rupture is at the inferior end of the esophagus and on the left. Initially, severe lower substernal or upper abdominal pain with associated shock may be preponderant. Diagnostic confusion with more frequently encountered conditions of the thorax or upper abdomen is common. Subsequently the features of mediastinitis, with usually an associated hydropneumothorax, predominate. The fulminating course and high mortality in untreated patients make early recognition and operative intervention urgent.A review of the Evanston Hospital records prior to 1946 failed to disclose a reported case of spontaneous rupture of the esophagus. Since that time nine such instances have been encountered. These cases form the basis of this report.Background  Rupture of SN - 0096-6908 M3 - doi: 10.1001/archsurg.1959.04320060066009 UR - http://dx.doi.org/10.1001/archsurg.1959.04320060066009 ER -