TY  - JOUR
T1  - PRospective phase i trial of conservative management of low rectal lesions
AU  - McCready DR, Ota DM, Rich TA, Thielvoldt D, Jessup J
Y1  - 1989/01/01
N1  - 10.1001/archsurg.1989.01410010077016
JO  - Archives of Surgery
SP  - 67
EP  - 70
VL  - 124
IS  - 1
N2  - • The purpose of this study was to assess anal function and to compare the morbidity of local excision and postoperative radiotherapy for rectal adenocarcinoma with the morbidity of abdominoperineal resection. A posterior parasacral approach was used for local excision. All patients had negative margins, and all but one were continent after completion of radiotherapy. Seven patients (29%) had either a wound infection or a fistula in the local excision group. No local failures occurred, although follow-up was only 13 months. Thirteen (50%) of the 26 patients who underwent an abdominoperineal resection developed at least one complication. Combined treatment that spares the rectal sphincters may be preferable in selected patients with low rectal cancer, if long-term disease-free survival is maintained.(Arch Surg 1989;124:67-70)
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.1989.01410010077016
UR  - http://dx.doi.org/10.1001/archsurg.1989.01410010077016
ER  -