TY - JOUR T1 - INfluence of estrogen receptors on survival and recurrence in patients with breast cancer without lymph node metastases AU - Maki HS, Hoehn JL Y1 - 1989/03/01 N1 - 10.1001/archsurg.1989.01410030127021 JO - Archives of Surgery SP - 377 EP - 380 VL - 124 IS - 3 N2 - • A retrospective chart review was conducted to determine the prognostic effect of estrogen receptor (ER) protein in patients with node-negative operable breast cancer. One hundred nine patients with breast cancer whose tumors underwent ER analysis and whose lymph node negativity was established histologically were studied. Based on life-table analysis, the overall survival at six years was 92.7% for ER-positive patients, 95.3% for ER-negative patients, and 94.4% for ER-borderline patients. The disease-free survival was 83.3%, 92.8%, and 71.4%, respectively. Survival and diseasefree survival were also correlated to menopausal status. The difference in survival was not statistically significant at six years. We conclude that in node-negative primary operable breast cancer, ER status should not be used as a discriminant for adjuvant treatment.(Arch Surg 1989;124:377-380) SN - 0004-0010 M3 - doi: 10.1001/archsurg.1989.01410030127021 UR - http://dx.doi.org/10.1001/archsurg.1989.01410030127021 ER -