TY - JOUR T1 - STrategy in reoperative surgery for hyperparathyroidism AU - Cheung PY, Borgstrom A, Thompson NW Y1 - 1989/06/01 N1 - 10.1001/archsurg.1989.01410060038008 JO - Archives of Surgery SP - 676 EP - 680 VL - 124 IS - 6 N2 - • Eighty-three patients undergoing reoperations for hyperparathyroidism were studied. Preoperative diagnosis was reviewed, and localization was employed in selected patients. Cervical reexploration was carried out in a systematic manner, and mediastinotomy was required in 11 patients. Sixty patients had had previous parathyroid exploration. Missed adenomas were found in 34, of which 28 were single and 6 were double adenomas. Fourteen single adenomas were in normal locations and 14 were in ectopic locations. Seventeen patients had hyperplasia; 6 were wrongly diagnosed as adenoma, 3 had inadequate excision, 2 had supernumerary glands, and 6 had remnant hypertrophy. Three patients had recurrent carcinoma. Two had wrong diagnoses and 4 had uncertain diagnoses. Reoperation eliminated hypercalcemia in 71 patients (85.5%). Eight patients developed permanent hypoparathyroidism, and 1 had a permanent recurrent nerve palsy. Reoperative parathyroid surgery can be minimized with thorough initial cervical exploration, correct pathologic interpretation, and adequate parathyroid resection.(Arch Surg. 1989;124:676-680) SN - 0004-0010 M3 - doi: 10.1001/archsurg.1989.01410060038008 UR - http://dx.doi.org/10.1001/archsurg.1989.01410060038008 ER -