TY  - JOUR
T1  - PAtterns of relapse in 1001 consecutive patients with melanoma nodal metastases
AU  - Calabro A, Singletary S, Balch CM
Y1  - 1989/09/01
N1  - 10.1001/archsurg.1989.01410090061014
JO  - Archives of Surgery
SP  - 1051
EP  - 1055
VL  - 124
IS  - 9
N2  - • The impact of nodal tumor burden on patterns of relapse and survival was retrospectively analyzed in 1001 patients with stage III melanoma. The incidence of tumor recurrence within the node dissection field was lower in patients with 1 nodal metastasis (9%) or with no extranodal invasion (15%) than in patients with multiple involved nodes (15% to 33%) or connective tissue invasion (28%). Patients with 1 "positive" node (a node in which cancer was detected) had a 45% 5-year and 39% 10-year survival rate compared with patients who had 2 to 4 positive nodes (37% and 28%), 5 to 10 nodes (20% and 17%), more than 10 nodes (5% and 3%), or extranodal invasion (14% and 11%). The occurrence of in-transit metastases in 10% of patients after nodal dissection was not influenced by the extent of nodal tumor burden.(Arch Surg. 1989;124:1051-1055)
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.1989.01410090061014
UR  - http://dx.doi.org/10.1001/archsurg.1989.01410090061014
ER  -