TY  - JOUR
T1  - LOng-term antireflux medication use following pediatric nissen fundoplication
AU  - Lee SL, Sydorak RM, Chiu VY, Hsu J, Applebaum H, Haigh PI
Y1  - 2008/09/15
N1  - 10.1001/archsurg.143.9.873
JO  - Archives of Surgery
SP  - 873
EP  - 876
VL  - 143
IS  - 9
N2  - Hypothesis 
    Nissen fundoplication decreases the use of antireflux medications.Design 
    Retrospective cohort study using discharge abstract data and pharmacy data.Setting 
    Twelve regional Kaiser Permanente hospitals in southern California.Patients 
    Three hundred forty-two patients underwent Nissen fundoplication.Intervention 
    Nissen fundoplication.Main Outcome Measure 
    Use of antireflux medications.Results 
    The number of patients requiring antireflux medications decreased from 233 patients (68.1%) before Nissen fundoplication to 197 (57.6%) after Nissen fundoplication. Of the 233 patients, 176 (75.6%) were restarted on antireflux medications within 1 year after Nissen fundoplication. Use of antireflux medication decreased in neurologically healthy patients but was unchanged in neurologically impaired children.Conclusions 
    Use of antireflux medication decreased after Nissen fundoplication. Neurologically healthy children showed the biggest decrease in antireflux medication use after Nissen fundoplication.
SN  - 0004-0010
M3  - doi: 10.1001/archsurg.143.9.873
UR  - http://dx.doi.org/10.1001/archsurg.143.9.873
ER  -