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This phase 1 clinical trial reports that a new agent designed to inhibit the binding of superantigen exotoxins to T-helper 1 lymphocyte receptors was safe and effective at improving some outcomes among hospitalized patients with necrotizing soft tissue infections.
Aboagye et al examine the disparities that may exist in colorectal cancer screening and treatment by comparing the distribution of providers of these services in rural and urban counties in the United States.
Jafari et al examine the surgical trends and outcomes of colorectal cancer treatment in the elderly.
Mavros et al conduct a systematic review and meta-analysis to evaluate the available evidence regarding treatment and prognosis in patients with intrahepatic cholangiocarcinoma.
Huang et al investigate the association between levels of hepatitis B surface antigen (HBsAg) and the risk for tumor recurrence after curative surgery for hepatocellular carcinoma (HCC) in patients with low levels of hepatitis B virus DNA.
Interview with David I. Soybel, MD, author of Positive and Negative Volume-Outcome Relationships in the Geriatric Trauma Population
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Ruptured Juxtarenal Aortic Aneurysm
Preoperative imaging demonstrating juxtarenal aortic aneurysm with contained rupture.
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Editor's Audio Summary
February 25, 2014
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Man With Hypoechoic Lesion Abutting the Pancreas
A previously healthy, 37-year-old man presented for a routine physical examination during which a pulsatile mass in his midepigastrium was palpated. Abdominal ultrasonography showed a well-defined hypoechoic lesion abutting the pancreas.
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JAMA Surgery now has an online readers' discussion of published articles. Submit Comments by selecting the article Comments tab. Letters submitted for consideration for print and online (archival) publication but not accepted may be accepted for Readers Comment.
During 2014, we will be soliciting manuscripts on innovation in surgical safety and safety in surgical innovation. The editorial board has selected this topic as our year-long theme. We are interested in papers that focus on novel ways surgeons are making the whole process of operative intervention safer- perioperative assessment, intraoperative monitoring of procedures, postoperative care. Additionally, we are interested in how surgeons are developing new techniques and procedures assuring safe outcomes. Accepted manuscripts will be given priority publication. Please indicate in your cover letter that your manuscript is to be considered for this theme.
JAMA Surgery is the official publication for the Association of VA Surgeons and the Pacific Coast Surgical Association. Each year, the journal publishes issues dedicated to the annual meetings of these two societies.
Due to the overwhelmingly positive response to the JAMA Surgery Clinical Challenge, we have temporarily discontinued accepting new submissions for this feature. Requests for submissions will resume in late 2014.
International translations of Author Video Interviews
Author Lillian Min, MD, MSHS, discusses Long-term Postinjury Functional Recovery.
Author Ajay Jain, MD, discusses Expansion of Screening Mammography in the Veterans Health Administration: Implications for Breast Cancer Treatment.
Author Elise H. Lawson, MD, MSHS, discusses Risk Factors for Superficial vs Deep/Organ-Space Surgical Site Infections: Implications for Quality Improvement Initiatives.
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