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 Showing 1-20 of 90 Articles
Arturo J. Rios-Diaz, MD; Jimmy Lam, BS; Cheryl K. Zogg, MSPH, MHS

This Viewpoint assesses the current status of postdischarge data collection in US trauma registries.

Original Investigation 
Felice Giuliante, MD; Francesco Ardito, MD; Alfredo Guglielmi, MD; Luca Aldrighetti, MD; Alessandro Ferrero, MD; Fulvio Calise, MD; Stefano M. Giulini, MD; Elio Jovine, MD; Claudio Breccia, MD; Agostino M. De Rose, MD; Antonio D. Pinna, MD; Gennaro Nuzzo, MD
Includes: Supplemental Content

Importance  The prognostic value of lymph node (LN) assessment after liver resection for hilar cholangiocarcinoma (HC) is still controversial, and the number of LNs required to be removed to obtain adequate staging is not well defined.

Objectives  To evaluate the LN status in patients after liver ...

Original Investigation  FREE
Michael W. Wandling, MD, MS; Eric S. Hungness, MD; Emily S. Pavey, MA; Jonah J. Stulberg, MD, PhD, MPH; Ben Schwab, MD; Anthony D. Yang, MD; Michael B. Shapiro, MD; Karl Y. Bilimoria, MD, MS; Clifford Y. Ko, MD, MS, MSHS; Avery B. Nathens, MD, PhD
Includes: Supplemental Content

Importance  There are currently 2 widely accepted treatment strategies for patients presenting to the hospital with choledocholithiasis. However, the rate of use for each strategy in the United States has not been evaluated, and their trends over time have not been described. Furthermore, an optimal management strategy ...

Invited Commentary: Surgical Management of Choledocholithiasis: A Disappearing Skill; Feng Shen, MD; Timothy M. Pawlik, MD, MPH, PhD
Original Investigation 
Alexander C. Schwed, MD; Monica M. Boggs, MEd; Xuan-Binh D. Pham, MD; Drew M. Watanabe; Michael C. Bermudez, BS; Amy H. Kaji, MD, PhD; Dennis Y. Kim, MD; David S. Plurad, MD; Darin J. Saltzman, MD, PhD; Christian de Virgilio, MD

Importance  Acute cholangitis (AC), particularly severe AC, has historically required urgent endoscopic decompression, although the timing of decompression is controversial. We previously identified 2 admission risk factors for adverse outcomes in AC: total bilirubin level greater than 10 mg/dL and white blood cell count greater than 20 000 ...

Invited Commentary: Acute Cholangitis Management; Kenric M. Murayama, MD
Invited Commentary 
Feng Shen, MD; Timothy M. Pawlik, MD, MPH, PhD

In this issue of JAMA Surgery, Wandling et al1 reported a decrease in the use of both open and laparoscopic common bile duct exploration (LCBDE) for patients with choledocholithiasis. Corresponding to this decrease in LCBDE with laparoscopic cholecystectomy (LC), the authors noted a marked increase in ...

Invited Commentary 
Kenric M. Murayama, MD

The article by Schwed et al1 compared a more recent cohort of patients with acute cholangitis (AC) at 1 of the 2 institutions (validation cohort) with a historical group of similar patients (derivation cohort). Their prior study of the derivation cohort identified 3 independent admission risk factors ...

JAMA Surgery Clinical Challenge 
Dai-Yin Lu, MD; Jen Wei, MD, MSD; Ming-Chon Hsiung, MD

A 61-year-old man with progressive shortness of breath for 1 week and myocardial infarction 1 month earlier had progressive dyspnea at rest, tachycardia, and tachypnea. Transthoracic echocardiography showed a hypoechoic mass and CT showed a large crescentic hypodense lesion. What is your diagnosis?

Original Investigation 
Emily B. Devine, PhD, PharmD, MBA; Rafael Alfonso-Cristancho, MD, MSc, PhD; N. David Yanez, PhD; Todd C. Edwards, PhD; Donald L Patrick, PhD, MSPH; Cheryl A. L. Armstrong, RN, MPH; Allison Devlin, MS; Rebecca G. Symons, MPH; Mark H. Meissner, MD; Ellen L. T. Derrick, MD, MPH; Danielle C. Lavallee, PhD, PharmD; Larry G. Kessler, ScD; David R. Flum, MD, MPH; for the Comparative Effectiveness Research Translation Network (CERTAIN) Collaborative

Importance  Intermittent claudication (IC) is the most common presentation of infrainguinal peripheral artery disease. Both medical and revascularization interventions for IC aim to increase walking comfort and distance, but there is inconclusive evidence of the comparative benefit of revascularization given the possible risk of limb loss.


Original Investigation 
Neel A. Mansukhani, MD; Dustin Y. Yoon, MD, MS; Katherine A. Teter, MD; Vanessa C. Stubbs, MD; Irene B. Helenowski, PhD; Teresa K. Woodruff, PhD; Melina R. Kibbe, MD
Includes: Supplemental Content

Importance  Sex is a variable that is poorly controlled for in clinical research.

Objectives  To determine if sex bias exists in human surgical clinical research, to determine if data are reported and analyzed using sex as an independent variable, and to identify specialties in which the ...

Invited Commentary 
Julie A. Freischlag, MD; Michelle M. Silva, BA

The article by Mansukhani et al1 in this issue of JAMA Surgery reveals that, despite the introduction of the National Institutes of Health Revitalization Act of 1993 to ensure that female participants were included in clinical trials, males and females currently are not included in surgical clinical ...

Invited Commentary 
Philip P. Goodney, MD, MS; Matthew A. Corriere, MD, MS

In their article “Effectiveness of a Medical vs Revascularization Intervention for Intermittent Leg Claudication Based on Patient-Reported Outcomes” in this issue of JAMA Surgery, Devine and colleagues1 embark on a challenging task in surgical outcomes assessment in their study comparing medical and invasive treatments for patients ...

Alik Farber, MD; Robert T. Eberhardt, MD

Importance  Chronic critical limb ischemia, marked by intractable lower extremity ischemic rest pain and tissue loss, is a highly morbid condition that leads to the loss of ambulation and decreased quality of life. It is associated with a high risk of limb loss and mortality and presents ...

Research Letter 
Ramesh B. Batchu, PhD; Oksana V. Gruzdyn, BS; Aamer M. Qazi, PhD; Ebrahem M. Mahmud, BS; Gamal Mostafa, MD; Donald W. Weaver, MD; Scott A. Gruber, MD, PhD, MBA

This cell biology study compares cytotoxic T cell lysis of in vitro pancreatic cancer cells with vs without tumor antigen expression induced by cell-penetrating peptide.

Comment & Response 
Richard B. Reiling, MD

To the Editor Nurok and colleagues1 have presented an intuitive discussion on the management of complicated surgical cases, especially in the postoperative setting with a challenge to the “captain of the ship” doctrine. This doctrine or philosophy originally appeared in the surgical lexicon to indicate who was ...

Comment & Response 
Michael Nurok, MBChB, PhD; Nicholas Sadovnikoff, MD; Bruce Gewertz, MD

In Reply Far from being marginalized, the surgeon’s role on the health care team is both critical and central because only the surgeon is aware of all elements of the operation. In this regard, Dr Reiling raises important points about responsibility and teamwork in an era of increasingly ...

David I. Soybel, MD; Kayla Knuf, BS

This Viewpoint reports on the concept of the Perioperative Surgical Home.

Original Investigation 
G. Craig Wood, MS; Peter N. Benotti, MD; Clare J. Lee, MD, MHS; Tooraj Mirshahi, PhD; Christopher D. Still, DO; Glenn S. Gerhard, MD; Michelle R. Lent, PhD
Includes: Supplemental Content

Importance  Weight loss after bariatric surgery varies, yet preoperative clinical factors associated with long-term suboptimal outcomes are not well understood.

Objective  To evaluate the association between preoperative clinical factors and long-term weight loss after Roux-en-Y gastric bypass (RYGB).

Design, Setting, and Participants  From June 2001 ...

Invited Commentary: Difficulty of Predicting Long-term Weight Loss After Gastric Bypass; Amy Neville, MD, MSc, FRCSC
Invited Commentary 
Amy Neville, MD, MSc, FRCSC

Weight regain occurs in a significant number of patients following gastric bypass1 and continues to be a potential Achilles heel of the gastric bypass procedure. In this issue of JAMA Surgery, Wood et al2 provide an extensive case series with admirable follow-up to examine clinical ...

Invited Commentary 
Julie Ann Sosa, MD, MA

In the current era of value-based care and a rapid research kinetic, evidence-based guidelines have become increasingly important. For clinicians, patients, and payers, they are an important means of synthesizing a large body of sometimes contradictory evidence to support best practice recommendations. Variation in practice generally implies variation ...

Special Communication 
Scott M. Wilhelm, MD; Tracy S. Wang, MD, MPH; Daniel T. Ruan, MD; James A. Lee, MD; Sylvia L. Asa, MD, PhD; Quan-Yang Duh, MD; Gerard M. Doherty, MD; Miguel F. Herrera, MD, PhD; Janice L. Pasieka, MD; Nancy D. Perrier, MD; Shonni J. Silverberg, MD; Carmen C. Solórzano, MD; Cord Sturgeon, MD; Mitchell E. Tublin, MD; Robert Udelsman, MD, MBA; Sally E. Carty, MD
Includes: Supplemental Content

Importance  Primary hyperparathyroidism (pHPT) is a common clinical problem for which the only definitive management is surgery. Surgical management has evolved considerably during the last several decades.

Objective  To develop evidence-based guidelines to enhance the appropriate, safe, and effective practice of parathyroidectomy.

Evidence Review  A ...

Invited Commentary: Best Approach for Primary Hyperparathyroidism Surgery; Julie Ann Sosa, MD, MA

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