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 Showing 21-40 of 76 Articles
Original Investigation  FREE
Pragatheeshwar Thirunavukarasu, MD; Chetasi Talati, MD; Sumeet Munjal, MD; Kris Attwood, PhD; Stephen B. Edge, MD; Valerie Francescutti, MD, MSc

Importance  The American Joint Committee on Cancer (AJCC) has proposed the inclusion of pretreatment serum carcinoembryonic antigen (CEA) levels (C stage) into the conventional TNM staging system of colon cancer. The latter proposal has yet to be widely adopted because of the lack of long-term survival estimates ...

Invited Commentary: Carcinoembryonic Antigen Elevation for Colon Cancer Prognosis; Ramzi Amri, MD; David L. Berger, MD
Original Investigation 
Franz Yanagawa, MD; Martin Perez, MD; Ted Bell, MS; Rod Grim, MA; Jennifer Martin, PhD; Vanita Ahuja, MD, MPH
Includes: Supplemental Content

Importance  As robotic-assisted cardiac surgical procedures increase nationwide, surgeons need to be educated on the safety of the new modality compared with that of open technique.

Objective  To compare complications, length of stay (LOS), actual cost, and mortality between nonrobotic and robotic-assisted cardiac surgical procedures.

Design, ...

Original Investigation 
Meeghan Lautner, MD, MSc; Heather Lin, PhD; Yu Shen, PhD; Catherine Parker, MD; Henry Kuerer, MD, PhD; Simona Shaitelman, MD, EdM; Gildy Babiera, MD; Isabelle Bedrosian, MD
Includes: Supplemental Content

Importance  Although breast-conserving therapy (BCT) is an accepted modality for treatment of early-stage breast cancer, many women continue to undergo mastectomy. Detailing the factors associated with choice of BCT may assist with overcoming barriers in the use of this treatment modality.

Objective  To conduct a population-based ...

Invited Commentary: Ongoing Consequences of Disparities in Breast Cancer Surgery; Lisa A. Newman, MD, MPH
Invited Commentary 
Marco G. Patti, MD

Czarnetzki and colleagues1 conducted a single-center, double-blind, placebo-controlled clinical trial in 132 patients who underwent emergent surgery for trauma or conditions such as appendicitis and cholecystitis. The authors hypothesized that erythromycin given intravenously 15 minutes before intubation decreases the volume of gastric contents, potentially decreasing the risk ...

Thirunavukarasu and colleagues1 use data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) database to determine whether preoperative serum carcinoembryonic antigen (CEA) status, dichotomized as elevated (C1) or normal (C0), can become a staging component in colon cancer, the C stage, akin to the ...

Invited Commentary 
Lisa A. Newman, MD, MPH

It is an unfortunate reality that unequal access to care persists as a significant cause of health outcome disparities. In this issue of JAMA Surgery, Lautner et al1 use statistics from the National Cancer Data Base to document this public health concern in the setting of ...

Surgical Innovation 
P. Marco Fisichella, MD, MBA; Alberto Ferreres, MD; Marco G. Patti, MD
Research Letter 
Brandyn D. Lau, MPH, CPH; Michael B. Streiff, MD; Peter J. Pronovost, MD, PhD; Adil H. Haider, MD, MPH; David T. Efron, MD; Elliott R. Haut, MD, PhD

This study reports that, at academic medical centers, many common process measures are entirely dependent on resident physicians with minimal direct, real-time oversight or feedback from attending physicians.

Original Investigation 
Alessandro Paniccia, MD; Patrick Hosokawa, MS; William Henderson, PhD; Richard D. Schulick, MD, MBA; Barish H. Edil, MD; Martin D. McCarter, MD; Csaba Gajdos, MD
Includes: Supplemental Content

Importance  To our knowledge, this study reports on the largest cohort of long-term survivors (LTSs) (≥10 years) following a diagnosis of pancreatic ductal adenocarcinoma (PADC) and identifies the characteristics associated with LTS.

Objective  To determine patient, tumor, surgical, and sociodemographic characteristics associated with LTS.

Design, Setting, ...

Invited Commentary: Long-term Survival After Pancreatic Cancer; Mu Xu, MD, PhD; O. Joe Hines, MD
Original Investigation  FREE
Colorectal Writing Group for the Surgical Care and Outcomes Assessment Program–Comparative Effectiveness Research Translation Network (SCOAP-CERTAIN) Collaborative
Includes: Supplemental Content

Importance  Venous thromboembolism (VTE) is an important complication of colorectal surgery, but its incidence is unclear in the era of VTE prophylaxis.

Objective  To describe the incidence of and risk factors associated with thromboembolic complications and contemporary VTE prophylaxis patterns following colorectal surgery.

Design, Setting, and ...

Invited Commentary: Use of Venous Thromboembolism Rates as Hospital Quality Measures; Christian de Virgilio, MD; Jerry J. Kim, MD
Invited Commentary 
Mu Xu, MD, PhD; O. Joe Hines, MD

Pancreatic cancer is the most lethal cancer with nearly every patient diagnosed dying within the ensuing 12 months. Pancreatic cancer is projected to become the second leading cause of cancer-related death in the United States by 2030.1 Very rarely anecdotal reports on long-term survivors surface; however, such ...

Invited Commentary 
Christian de Virgilio, MD; Jerry J. Kim, MD

The Centers for Medicare & Medicaid Services will implement the Hospital Acquired Condition (HAC) Reduction Program in 2015, as mandated by the Patient Protection and Affordable Care Act. The effect will be a 1% reduction to Medicare payments for hospitals in the top quartile of risk-adjusted HAC rates. ...

Review  FREE
Susanne Hempel, PhD; Melinda Maggard-Gibbons, MD; David K. Nguyen, MD; Aaron J. Dawes, MD; Isomi Miake-Lye, BA; Jessica M. Beroes, BS; Marika J. Booth, MS; Jeremy N. V. Miles, PhD; Roberta Shanman, MLS; Paul G. Shekelle, MD, PhD
Includes: Supplemental Content

Importance  Serious, preventable surgical events, termed never events, continue to occur despite considerable patient safety efforts.

Objective  To examine the incidence and root causes of and interventions to prevent wrong-site surgery, retained surgical items, and surgical fires in the era after the implementation of the ...

JAMA Surgery Clinical Challenge 
Ian Solsky, MD; Oscar K. Serrano, MD; Sarah Bellemare, MD
Research Letter 
Anna Weiss, MD; Jamie E. Anderson, MD, MPH; David C. Chang, PhD, MBA, MPH

This study compares the National Surgical Quality Improvement Program with the Nationwide Inpatient Sample database to determine which is superior at performing analyses of risk-adjusted outcomes for several operations.

This Viewpoint describes the American Board of Surgery Maintenance of Certification Program.

This Viewpoint discusses the American Board of Internal Medicine’s recent changes to the Maintenance of Certification Program and plans for program revision.

Original Investigation 
Georgios Antonios Margonis, MD; Yuhree Kim, MD, MPH; Gaya Spolverato, MD; Aslam Ejaz, MD, MPH; Rohan Gupta, MD; David Cosgrove, MD; Robert Anders, MD; Georgios Karagkounis, MD; Michael A. Choti, MD; Timothy M. Pawlik, MD, MPH, PhD
Includes: Supplemental Content

Importance  Currently, one of the most commonly available biomarkers in the treatment of patients with colorectal liver metastases (CRLM) is the Kirsten rat sarcoma viral oncogene homolog (KRAS); however, the prognostic implications of specific mutations of the KRAS gene are still not well defined.


Original Investigation  FREE
Yasuaki Sagara, MD; Melissa Anne Mallory, MD; Stephanie Wong, MD; Fatih Aydogan, MD; Stephen DeSantis, BS; William T. Barry, PhD; Mehra Golshan, MD

Importance  While the prevalence of ductal carcinoma in situ (DCIS) of the breast has increased substantially following the introduction of breast-screening methods, the clinical significance of early detection and treatment for DCIS remains unclear.

Objective  To investigate the survival benefit of breast surgery for low-grade DCIS....

Invited Commentary: No Surgery for Low-Grade Ductal Carcinoma In Situ?; Julie A. Margenthaler, MD; Aislinn Vaughan, MD
Original Investigation 
Kristina H. Lewis, MD, MPH, SM; Fang Zhang, PhD; David E. Arterburn, MD, MPH; Dennis Ross-Degnan, ScD; Matthew W. Gillman, MD, SM; J. Frank Wharam, MB, BCh, BAO, MPH
Includes: Supplemental Content

Importance  There is conflicting evidence about how different bariatric procedures impact health care use.

Objective  To compare the impact of laparoscopic adjustable gastric banding (AGB) and laparoscopic Roux-en-Y gastric bypass (RYGB) on health care use and costs.

Design, Setting, and Participants  Retrospective interrupted time series ...

Invited Commentary: Does Bariatric Surgery Reduce Health Care Costs?; Justin B. Dimick, MD, MPH

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