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 Showing 21-40 of 101 Articles
Invited Commentary 
John A. Windsor, MD, FRACS

Katz and colleagues are to be congratulated in establishing the multicenter Alliance for Clinical Trials in Oncology, which seeks to address, in part, the paucity of quality evidence supporting neoadjuvant therapy (NAT) for borderline resectable pancreatic cancer (BRPC).1 Their preliminary study is about feasibility, quality control, and ...

Susan Tsai, MD, MHS; Douglas B. Evans, MD

Importance  It is estimated that pancreatic cancer (PC) will become the second leading cause of cancer-related death in the United States by 2030.

Observations  Clinical and preclinical data support the understanding that PC metastases occur early in the pathogenesis of this disease, even before the primary ...

Surgical Innovation 
H. Randall Beard, MD; Alejandro J. Marquez-Lara, MD; Kamran S. Hamid, MD, MPH

This article discusses the use of wearable, high-definition cameras to create a surgical skills video library to improve resident training.

JAMA Surgery Clinical Challenge 
Hao-Yu Lin, MD; Yuan-Huei Huang, MD, PhD; Ming-Chi Yang, MD

An 84-year-old woman presented with 2 days of progressive abdominal distention and nausea, a distended abdomen without peritoneal signs on examination, an elevated white blood cell count, and segmental small-bowel dilatation on abdominal x-ray. What is your diagnosis?

Shinichiro Sakata, MBBS; Philip M. Grove, PhD; Andrew R. L. Stevenson, MBBS, FRACS

This Viewpoint discusses the differences between 3-dimensional robotic surgery and conventional 2-dimensional laparoscopic surgery.

Original Investigation 
Davide Citterio, MD; Antonio Facciorusso, MD; Carlo Sposito, MD; Roberta Rota, MD; Sherrie Bhoori, MD; Vincenzo Mazzaferro, MD, PhD
Includes: Supplemental Content

Importance  Liver resection is the treatment of choice for hepatocellular carcinoma (HCC) in well-compensated liver cirrhosis. Postoperative liver decompensation (LD) is the most representative and least predictable cause of morbidity and mortality.

Objectives  To determine the hierarchy and interaction of factors associated with the risk for ...

Invited Commentary: Decision Tree of Liver Resection for Hepatocellular Carcinoma; Jacqueline M. Garonzik-Wang, MD, PhD; Maria B. Majella Doyle, MD, MBA, FRCS
Original Investigation 
Lwin Aung, FRCSEd; Wei-Jei Lee, MD, PhD; Shu Chun Chen, RN; Kong-Han Ser, MD; Chun-Chi Wu, MD; Keong Chong, MD; Yi-Chih Lee, PhD; Jung-Chien Chen, MD
Includes: Supplemental Content

Importance  The prevalence of early-onset type 2 diabetes mellitus (T2DM), which responds poorly to medical treatment, is increasing. Bariatric surgery has been well recognized for its effectiveness in the remission of T2DM, but its effectiveness and durability in the remission of early-onset T2DM has not yet been ...

Invited Commentary: Early Bariatric Surgery for Diabetes in Obesity; David A. Harris, MD; Ali Tavakkoli, MD
Invited Commentary 
David A. Harris, MD; Ali Tavakkoli, MD

The article by Aung et al1 in this issue of JAMA Surgery continues the excellent clinical research from the group in Taiwan. Multiple randomized studies have demonstrated the efficacy of bariatric surgery in treating type 2 diabetes (T2D), and the term metabolic surgery is being increasingly used, ...

Invited Commentary 
Jacqueline M. Garonzik-Wang, MD, PhD; Maria B. Majella Doyle, MD, MBA, FRCS

The incidence of hepatocellular carcinoma in the United States has grown steadily during the past 2 decades and the associated mortality has increased proportionally.1 In 2012, there were an estimated 30 000 new cases of liver cancer and 24 000 liver cancer–associated deaths.2 Underlying liver disease associated with ...

Research Letter 
Cornelius A. Thiels, DO; Kristine T. Hanson, MPH; Stephanie F. Heller, MD; Martin D. Zielinski, MD; Elizabeth B. Habermann, PhD

This case series examines surgical patients’ perceptions of care in July and August, with the influx of new surgical residents, vs the rest of the year.

Original Investigation 
Brodie A. Parent, MD; Max Seaton, MD; Ravi F. Sood, MD, MS; Haiwei Gu, PhD; Danijel Djukovic, PhD; Daniel Raftery, PhD; Grant E. O’Keefe, MD, MPH
Includes: Supplemental Content

Importance  Metabolomics is the broad and parallel study of metabolites within an organism and provides a contemporaneous snapshot of physiologic state. Use of metabolomics in the clinical setting may help achieve precision medicine for those who have experienced trauma, where diagnosis and treatment are tailored to the ...

Importance  Thyroid cancer incidence is increasing, and when fine-needle aspiration biopsy results are cytologically indeterminate, the diagnosis is often still established only after thyroidectomy. Molecular marker testing may be helpful in guiding patient-oriented and tailored management of thyroid nodules and thyroid cancer.

Objective  To summarize available ...

Surgical Innovation 
Jamii St Julien, MD, MPH; Nancy D. Perrier, MD

This article reports on how video telementoring is likely to play an increasing role in surgical education.

Research Letter 
Joshua D. Rouch, MD; Jessica A. Keeley, MD; Andrew Scott, MD; Roman Sydorak, MD; Daniel DeUgarte, MD; Steven L. Lee, MD

This case series compares unroofing and marsupialization vs wide local excision as surgical therapy for pilonidal disease.

Correction  FREE

In the Research Letter titled “Comparing Publicly Reported Surgical Outcomes With Quality Measures From a Statewide Improvement Collaborative,”1 published online March 16, 2016, the first sentence of the figure legend miscategorized the methods used by the Surgeon Scorecard. The sentence should read as follows: “The complication rate ...

Original Investigation 
Caitlin W. Hicks, MD, MS; Joseph K. Canner, MHS; Isibor Arhuidese, MD, MPH; Tammam Obeid, MD; James H. Black III, MD; Mahmoud B. Malas, MD, MHS

Importance  Patient- and hospital-level factors affecting outcomes after open and endovascular abdominal aortic aneurysm (AAA) repair are each well described separately, but not together.

Objective  To describe the association of patient- and hospital-level factors with in-hospital mortality after elective AAA repair.

Design, Setting, and Participants  ...

Invited Commentary: Aortic Centers of Excellence; Edward D. Gifford, MD; Christian de Virgilio, MD
Original Investigation 
Joaquim M. Havens, MD; Alexandra B. Columbus, MD; Olubode A. Olufajo, MD, MPH; Reza Askari, MD; Ali Salim, MD; Kenneth B. Christopher, MD, SM

Importance  Emergency general surgery (EGS) patients have a disproportionate burden of death and complications. Chronic liver disease (CLD) increases the risk of complications following elective surgery. For EGS patients with CLD, long-term outcomes are unknown and risk stratification models do not reflect severity of CLD.

Objective  ...

Invited Commentary: Mind MELD or Ignore It at Your Peril; Ali Zarrinpar, MD, PhD
Invited Commentary 
Edward D. Gifford, MD; Christian de Virgilio, MD

The Leapfrog initiative was created with the goal of improving in-hospital mortality for high-risk procedures, including elective abdominal aortic aneurysm (AAA) repair.1 The aim was to lower perioperative AAA mortality by at least 50% by referring patients to high-volume centers because high volume was felt to be ...

Invited Commentary 
Ali Zarrinpar, MD, PhD

Chronic liver disease (CLD) and its attendant increased risk of operative mortality and morbidity give appropriate pause to many surgeons and patients prior to undertaking any operation, especially an emergency. While the American College of Surgeons National Surgical Quality Improvement Project Surgical Risk Calculator1 does not yet ...

JAMA Surgery Clinical Challenge 
Run-De Jiang, MD; Zong-Li Zhang, MD; Tao Li, MD

A man in his mid-50s was referred to our hospital because he had a cystic mass in his spleen that was discovered incidentally during a routine physical examination. He had no history of abdominal trauma, infection, or surgery. What is your diagnosis?

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