This secondary analysis of the TRIO-013 phase 3 randomized clinical trial attempts to determine if gastric acid suppressants such as proton pump inhibitors may impair capecitabine efficacy.
This meta-analysis examines the association between recurrent Clostridium difficile infection and use of gastric acid suppressant medications.
This Viewpoint addresses the increasing incidence of drug-drug interactions with personalized cancer treatment drugs.
This pharmacoepidemiology study uses Medicare Part D data to describe changes in use of prescription drugs associated with an increase in fracture risk before and after fragility fractures.
This cross-sectional analysis uses data from the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey to determine whether chronic rhinosinusitis is associated with administration of antireflux medications.
This case report describes 2 patients with sticky palms as an adverse effect of proton-pump inhibitors.
This cross-sectional study estimates potential savings through therapeutic substitution in terms of both overall and out-of-pocket expenditures of branded drugs when a generic in the same class with the same indication was available.
This quasi-experimental controlled study investigates the effect of detecting and isolating Clostridium difficile asymptomatic carriers at hospital admission on the incidence of health care–associated C difficile infection in a Canadian acute care facility.
This study characterizes the histologic features of esophageal inflammation in patients with acute gastroesophageal reflux disease during and after discontinuation of proton pump inhibitor treatment.
This case of a woman in her 60s presenting with ear fullness and asymetric hearing loss is a reminder to carefully consider indications for treatment using proton pump inhibitors in the setting of steroid use.