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  • Imminent Death Liver Donation for Children: Potential to Meet an Unmet Need

    Abstract Full Text
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    JAMA Surg. 2017; doi: 10.1001/jamasurg.2017.3793

    This Viewpoint proposes a new process, imminent death donation, to correct a chronic shortage of livers available for pediatric transplantation.

  • JAMA Surgery August 1, 2016

    Figure: Hospital Surgical Site Infection (SSI) Performance by Hospital Summary Score

    Hospital quality summary score includes the following variables: (1) inpatient admission volume, (2) Joint Commission accreditation, (3) Commission on Cancer accreditation, (4) presence of transplant services, (5) level I trauma center status, (6) nurse to bed ratio, (7) Council of Teaching Hospitals membership, and (8) clinical surgical registry participation. SIR indicates standardized infection ratio (risk-adjusted observed to expected ratio for hospital-acquired infections [a score of <1 indicates fewer infections than expected, a score of 1 indicates an expected number of infections, and a score of >1 indicates more infections that expected.]). Error bars indicate 95% CIs.aDetermined by use of the Cochran-Armitage test for trends.
  • Hepatopancreatobiliary Surgery Fellowships: How Many Do We Need?

    Abstract Full Text
    JAMA Surg. 2016; 151(3):213-214. doi: 10.1001/jamasurg.2015.4601

    This Viewpoint discusses the growing number of hepatopancreatobilary surgery fellowships and emphasizes the need for standardization of training requirements.

  • Effect of Liver Transplant on Long-term Disease-Free Survival in Children With Hepatoblastoma and Hepatocellular Cancer

    Abstract Full Text
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    JAMA Surg. 2015; 150(12):1150-1158. doi: 10.1001/jamasurg.2015.1847

    This case series assesses the efficacy of liver transplantation in children with advanced hepatocellular carcinoma or hepatoblastoma.

  • Damage Control as a Strategy to Manage Postreperfusion Hemodynamic Instability and Coagulopathy in Liver Transplant

    Abstract Full Text
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    JAMA Surg. 2015; 150(11):1066-1072. doi: 10.1001/jamasurg.2015.1853

    This case serues of patients undergoing liver transplant reports on damage control as a viable strategy for liver transplant recipients with coagulopathy or hemodynamic instability after allograft reperfusion.

  • JAMA Surgery November 1, 2015

    Figure 1: Flow Diagram of Study Patients

    Of 150 patients who underwent damage control (DC), 58 had a single, planned additional operation for delayed biliary reconstruction (DBR), 26 had a single, unplanned additional operation during which the bile duct was reconstructed, and 57 had multiple additional operations for various complications. Five patients died before any additional operation, and 4 patients underwent additional transplant at the first additional operation. OLT indicates orthotopic liver transplant.
  • Association Between Prolonged Graft Ischemia and Primary Graft Failure or Survival Following Lung Transplantation

    Abstract Full Text
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    JAMA Surg. 2015; 150(6):547-553. doi: 10.1001/jamasurg.2015.12

    This retrospective study shows that prolonged ischemia is not associated with primary graft failure or survival following lung transplantation. See also the Invited Commentary by Bharat.

  • JAMA Surgery April 1, 2015

    Figure 2: Survival Rates After Liver Transplantation

    Survival rates of patients with a diagnosis of benign solid liver tumors who underwent transplantation, by age (P = .005).
  • Role of Transplantation in the Treatment of Benign Solid Tumors of the Liver: A Review of the United Network of Organ Sharing Data Set

    Abstract Full Text
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    JAMA Surg. 2015; 150(4):337-342. doi: 10.1001/jamasurg.2014.3166

    This retrospective analysis shows that liver transplantation is a valid therapeutic option in selected patients with benign solid liver tumors who are not amenable to resection.

  • Survival Benefit of Solid-Organ Transplant in the United States

    Abstract Full Text
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    JAMA Surg. 2015; 150(3):252-259. doi: 10.1001/jamasurg.2014.2038

    This retrospective analysis demonstrated that more than 2 million life-years were saved by solid-organ transplants during a 25-year study period.

  • Autologous Islet Transplantation With Remote Islet Isolation After Pancreas Resection for Chronic Pancreatitis

    Abstract Full Text
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    JAMA Surg. 2015; 150(2):118-124. doi: 10.1001/jamasurg.2014.932

    This retrospective cohort study finds that pancreatic resection with autologous islet transplantation for severe chronic pancreatitis is a safe and effective final alternative to ameliorate debilitating pain and to help prevent the development of surgical diabetes.

  • Chronic Intestinal Failure After Crohn Disease: When to Perform Transplantation

    Abstract Full Text
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    JAMA Surg. 2014; 149(10):1060-1066. doi: 10.1001/jamasurg.2014.1072

    Gerlach and coauthors explore the limitations of conventional surgery and the decision-making process for transplantation.

  • JAMA Surgery October 1, 2014

    Figure: Description of the Study Cohort

    Description of the study cohort of 2 intestinal transplantation (ITx) and rehabilitation centers: 10 patients underwent transplantation, and the other 10 were on the waiting list or elected not to undergo transplantation and were therefore unavailable for follow-up. One patient underwent conventional surgery and 1 was taken off the waiting list. The mean (SD) calculated scores of all subgroups are indicated in parentheses. AWT indicates abdominal wall transplantation; KTx, kidney transplantation; and MVTx, multivisceral transplantation.
  • The Impact of Meeting Donor Management Goals on the Number of Organs Transplanted per Expanded Criteria Donor: A Prospective Study From the UNOS Region 5 Donor Management Goals Workgroup

    Abstract Full Text
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    JAMA Surg. 2014; 149(9):969-975. doi: 10.1001/jamasurg.2014.967

    Patel and coauthors determine the effect of meeting a standardized set of critical care end points, or donor management goals, on the number of organs transplanted per donor using expanded criteria donors. See the Invited Commentary by Salim.

  • Effect of Community Educational Interventions on Rate of Organ Donation Among Hispanic Americans

    Abstract Full Text
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    JAMA Surg. 2014; 149(9):899-902. doi: 10.1001/jamasurg.2014.1014

    Salim and colleagues investigate the effect of an aggressive outreach intervention during a 5-year period aimed at improving organ donation rates among Hispanic Americans. See also the invited commentary by Malinoski.

  • Neonates With Short Bowel Syndrome: An Optimistic Future for Parenteral Nutrition Independence

    Abstract Full Text
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    JAMA Surg. 2014; 149(7):663-670. doi: 10.1001/jamasurg.2013.4332

    Fallon et al determine the probability of wean from parenteral nutrition (PN) in neonates with short bowel syndrome (SBS) based on small intestinal length amidst the new era of hepatoprotective strategies and multidisciplinary management.

  • JAMA Surgery July 1, 2014

    Figure 3: Cumulative Probability of Weaning From Parenteral Nutrition (PN) Over Time

    A, Cumulative probability of wean based on small intestinal length. B, Cumulative probability of wean based on percentage of predicted length. Patients who died (n = 8) or underwent transplant (n = 4) were excluded. IQR indicates interquartile range.
  • JAMA Surgery July 1, 2014

    Figure 2: Predicted Probability of Weaning From Parenteral Nutrition (PN)

    A, Predicted probability based on small intestinal length. B, Predicted probability based on percentage of predicted small intestinal length. C, Predicted probability based on small intestinal length excluding patients who underwent bowel-lengthening procedures. The curved black line indicates predicted probability. Patients who died (n = 8) or underwent transplant (n = 4) were excluded.
  • Liver Transplantation in Children Using Organ Donation After Circulatory Death: A Case-Control Outcomes Analysis of a 20-Year Experience in a Single Center

    Abstract Full Text
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    JAMA Surg. 2014; 149(1):77-82. doi: 10.1001/jamasurg.2013.3195

    Hong et al compare long-term outcomes for children (aged ≤18 years) undergoing orthotopic liver transplantation using grafts from donation after circulatory death and donation after brain death.

  • Regulatory Oversight in Transplantation: There and Back Again

    Abstract Full Text
    JAMA Surg. 2013; 148(11):997-998. doi: 10.1001/jamasurg.2013.2762